An extract from the ginseng berry shows real promise in treating diabetes and obesity, reports a research team from the University of Chicago’s Tang Center for Herbal Medicine Research. In the June issue of the journal Diabetes, they show that the extract completely normalized blood glucose levels, improved sensitivity to insulin, lowered cholesterol levels, and decreased weight by reducing appetite and increasing activity levels in mice bred to develop diabetes.

For more than 2000 years, traditional Chinese medicine has used ginseng root to treat a variety of ailments. This study focused instead on substances found in the ginseng berry, which has very different concentrations of ginsenosides, the substances thought to be medically useful.

“This novel compound could serve as the basis for a whole new class of anti-diabetic medications,” said Yuan, who is also working to isolate other substances from the extract that contributed to the weight loss.

There is a pressing need for new and more effective drugs for both diabetes and obesity. Obesity – weighing more than 20 percent over your maximum recommended body weight – contributes to an estimated 300,000 deaths each year.

“Since this berry contains agents that are effective against both obesity and diabetes, the ginseng fruit has enormous promise as a source of new drugs,” said Yuan, who has worked with the University to apply for a patent on the development of ginsenoside Re as a diabetes medication.

Eurekalert.org
Ginseng berry extract shows promise for diabetes, obesity
The research was funded by the Tang Family Foundation & the National Institutes of Health
24 May 2002